
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
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Product Description
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.
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